Adaptive radiation therapy by X. Allen Li

By X. Allen Li

Modern scientific imaging and radiation treatment applied sciences are so advanced and computing device pushed that it really is tough for physicians and technologists to understand precisely what's taking place on the point-of-care. clinical physicists accountable for filling this hole in wisdom needs to remain abreast of the most recent advances on the intersection of scientific imaging and radiation treatment. This ebook offers scientific physicists and radiation oncologists present and suitable info on Adaptive Radiation remedy (ART), a cutting-edge technique that makes use of a suggestions strategy to account for patient-specific anatomic and/or organic alterations, therefore offering hugely individualized radiation remedy for melanoma sufferers. The e-book also needs to profit scientific dosimetrists and radiation therapists.

Adaptive Radiation Therapy

describes technological and methodological advances within the box of paintings, in addition to preliminary scientific stories utilizing artwork for chosen anatomic websites. Divided into 3 sections (radiobiological foundation, present applied sciences, and medical applications), the booklet covers:

  • Morphological and organic biomarkers for patient-specific planning
  • Design and optimization of remedies
  • Delivery of IMRT and IGRT intervention methodologies of ART
  • Management of intrafraction diversifications, rather with breathing movement
  • Quality insurance had to make sure the secure supply of artwork
  • ART functions in different universal melanoma kinds / anatomic websites

The know-how and technique for paintings have complex considerably within the previous couple of years and gathered scientific info have tested the necessity for paintings in scientific settings, assisted via the vast program of depth modulated radiation remedy (IMRT) and image-guided radiation treatment (IGRT). This booklet exhibits the genuine strength for offering each sufferer with individualized radiation remedy that's maximally exact and precise.

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Marchal, and P. Suetens. 1999. Reduction of metal streak artifacts in X-ray computed tomography using a transmission maximum a posteriori algorithm. IEEE Nuclear Science Symposium Conference Record 2:850–4. Donoho, D. L. 2006. Compressed sensing. IEEE Trans Inf Theory 52:1289–306. Adaptive Radiation Therapy Feldkamp, L. , L. C. Davis, and J. W. Kress. 1984. Practical conebeam algorithm. J Opt Soc Am A 1:612–9. Fessler, J. A. 1994. Penalized weighted least-squares image­reconstruction for positron emission tomography.

The central idea is that, given the projection data at two angles and two phases (assume that the angular and temporal separations are relatively small), it is possible, to a certain degree, to derive the projection at an intermediate phase and angle through spatial–temporal interpolation. In other words, the reconstruction of a phase will consider not only the projections corresponding to that phase but also those corresponding to other phases. As a result, the number of gantry rotations needed to obtain a decent 4D CBCT image will be greatly reduced.

Compressed sensing. IEEE Trans Inf Theory 52:1289–306. Adaptive Radiation Therapy Feldkamp, L. , L. C. Davis, and J. W. Kress. 1984. Practical conebeam algorithm. J Opt Soc Am A 1:612–9. Fessler, J. A. 1994. Penalized weighted least-squares image­reconstruction for positron emission tomography. IEEE Trans Med Imaging 13:290–300. , T. Kohler, and R. Proksa. 2000. 3D cone-beam CT reconstruction for circular trajectories. Phys Med Biol 45:329–47. , T. Kohler, and R. Proksa. 2001. Angular weighted hybrid cone-beam CT reconstruction for circular trajectories.

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